Fridays is a GLP-1 weight loss telehealth platform offering compounded semaglutide from $150/mo and tirzepatide, plus brand-name Ozempic and Zepbound, with an insurance concierge, FSA/HSA eligibility, and bundled dietitian and coaching support.
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Complete 2026 Comparison for Weight Loss
TrimRx is our overall pick for weight loss, based on our rating and feature coverage.
Fridays is a GLP-1 weight loss telehealth platform offering compounded semaglutide from $150/mo and tirzepatide, plus brand-name Ozempic and Zepbound, with an insurance concierge, FSA/HSA eligibility, and bundled dietitian and coaching support.
TrimRx is a telehealth weight loss platform offering compounded GLP-1 medications - semaglutide from $149/month and tirzepatide from $249/month - with licensed physician oversight, sourcing through licensed 503A compounding pharmacies, and a money-back guarantee.
| Feature | ||
|---|---|---|
| Rating | 9.2/10 | 9.4/10 |
| Founded | 2023 | 2020 |
| Free Consultation | Yes | Yes |
| Free Shipping | Yes | Yes |
| Accepts Insurance | No | No |
| HSA/FSA Accepted | Yes | Yes |
| Mobile App | No | No |
| Consultation Type | Asynchronous | Async (text/questionnaire) |
| Shipping Time | 3-5 business days | 3-5 business days |
| Treatment | ||
|---|---|---|
| Weight Loss | $150/month$150-$279/month | $179/month$179-$249/month |
The better choice depends on your specific needs and priorities. Fridays carries a 9.2/10 rating in our provider database and is listed as a fit for value-seekers who want low compounded glp-1 pricing. TrimRx carries a 9.2/10 rating in our provider database and is listed as a fit for patients wanting the lowest monthly glp-1 cost. Those scores are our own editorial ratings, not third-party review averages. Fridays was founded in 2023 in United States, while TrimRx was founded in 2020 in United States. Both are US telehealth platforms that connect you with licensed providers, and which one suits you is a question for that provider.
Pricing varies by treatment category. Fridays starts at $150/month (range: $150-$279/month). TrimRx starts at $179/month (range: $179-$249/month). These are the rates last recorded in our provider database, so confirm the current price at checkout before you enroll. Fridays lists free consultations. TrimRx lists free consultations. Fridays lists free shipping. TrimRx lists free shipping. Fridays and TrimRx list HSA and FSA payment options, though whether a given charge is eligible depends on your plan and on IRS rules for that expense.
Fridays does not list health insurance as accepted, and operates on a cash-pay model with published pricing. TrimRx does not list insurance as accepted. Fridays and TrimRx list HSA and FSA payment options; eligibility for any specific charge depends on your plan and IRS rules, so check with your plan administrator first. Coverage and pricing change, so confirm both with the platform and your insurer before you enroll.
Both are established US telehealth platforms. Fridays was founded in 2023 and is headquartered in United States. TrimRx was founded in 2020 in United States. Both state that they work with US-licensed providers and licensed pharmacies and that they operate under HIPAA. We do not independently audit provider credentials or pharmacy licensing, so if you want that confirmed, you can look up an individual prescriber through your state medical board and a pharmacy through your state board of pharmacy.
Fridays offers asynchronous consultations (free). TrimRx provides async (text/questionnaire) consultations (free). On both, you complete a health questionnaire online that a licensed provider reviews. Turnaround times vary by platform, by state, and by how busy the provider network is, and you can message your provider with follow-up questions through the platform.
Fridays lists shipping within 3-5 business days with free standard shipping. TrimRx lists shipping within 3-5 business days with free standard shipping. Both describe discreet packaging, and medications ship from licensed pharmacies rather than from the platform itself. Actual delivery time depends on your state, the pharmacy, and whether your prescription needs follow-up.
Fridays requires a subscription for most treatments and lists cancellation at any time without a fee. TrimRx also uses a subscription model and lists no cancellation penalty. Cancellation terms are set by each platform and can change, so read the current terms before you enroll. As a general rule you need to cancel before your next billing date to avoid the following period's charge, and anything already shipped is still yours.
Fridays lists Compounded Semaglutide, Compounded Tirzepatide, Brand-Name Ozempic & Zepbound, GLP-1 Microdosing starting at $150/month. TrimRx lists Compounded Semaglutide, Compounded Tirzepatide starting at $179/month. Wegovy (semaglutide) and Zepbound (tirzepatide) are the brand-name injectables FDA-approved for weight management. Where a program dispenses compounded semaglutide or tirzepatide instead, that is a pharmacy-prepared drug rather than the approved finished product. Compounded drugs are not FDA-approved and have not been reviewed by the FDA for safety, effectiveness, or quality. Programs typically bundle medication, provider consultations, and check-ins, and they differ mainly on price, on which medications they carry, and on how much support is included. Whether any of this is appropriate for you is a question for a licensed provider.
Side effects come from the medication, not from the platform, so this is mostly a question about the drug you end up on rather than about Fridays versus TrimRx. Reported effects vary by treatment: ED medications may cause headache, flushing, or nasal congestion; finasteride carries labeled sexual side effects that some men report persisting after they stop; GLP-1 medications commonly cause nausea, vomiting, and other gastrointestinal effects, especially when the dose goes up; SSRIs may cause drowsiness, nausea, or changes in appetite and sexual function. This is not the full list for any of them. Both platforms have licensed providers review your medical history and screen for contraindications, and you should read the medication guide and raise anything you notice with your provider.
Choose Fridays if you prioritize: value-seekers who want low compounded glp-1 pricing, people without glp-1 insurance coverage. Choose TrimRx if you prioritize: patients wanting the lowest monthly glp-1 cost, those who want a money-back guarantee. Fridays stands out for: Insurance concierge for coverage. TrimRx is known for: Money-back guarantee if you do not lose weight. Both are established telehealth platforms, so your choice mostly comes down to price, which treatments each one carries, and how you prefer to handle visits and refills.
The process is similar on both. For Fridays: visit their website, select your treatment category, and complete a health questionnaire that a licensed provider reviews. For TrimRx: follow the same kind of flow on their platform. Both ask for your medical history, current medications, and answers to health screening questions, and being straight with those answers is what lets the provider catch an interaction. If you are approved, the prescription goes to a licensed pharmacy and ships to you (often with free shipping). How long the whole thing takes depends on the platform, your state, and the pharmacy.
Fridays carries a 9.2/10 rating in our provider database, and TrimRx carries a 9.2/10 rating in our provider database. Those are ManyTreatments editorial scores on a 10-point scale, not averages pulled from third-party review sites, and you can read how we build them on our how-we-rate page. What we weigh: Fridays scores well on compounded semaglutide from $150/mo on a prepaid plan, with $150/mo requires a prepaid plan; month-to-month is $249/mo as the trade-off. For TrimRx it is lowest price in market at $149/month for semaglutide, against weight loss only - no multi-condition coverage. If you want customer sentiment as well, check current listings on the review platforms directly, since those move.
Medical Disclaimer: The information on this page is for educational purposes only and is not medical advice. Always consult with a licensed healthcare provider before starting any treatment. Read our full medical disclaimer.
Regulatory noticeRegulatory note (verified August 22, 2026): On February 20, 2026 the FDA issued MEDVi, LLC a warning letter (MARCS-CMS 721455) citing misbranding under sections 502(a) and 502(bb) of the FD&C Act. Reviewing medvi.io in December 2025, the FDA said labels bearing "MEDVi" implied MEDVi compounds the drugs when it does not, and that "Same active ingredient as Wegovy and Ozempic" and "Same active ingredient as Mounjaro and Zepbound" implied an FDA approval compounded drugs do not have. We found no close-out letter, so the matter appears open. MEDVi states medvi.io is affiliate-operated rather than company-operated; we could not verify that, and the letter is addressed to MEDVi, LLC. Read the FDA letter