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  1. Home
  2. Compare
  3. MyStart Health vs TrimRx
Eric GoldWritten by Eric GoldEditor-in-Chief
MyStart Health telehealth platform
MyStart Health
VS
TrimRx telehealth platform
TrimRx
Read Our MyStart Health ReviewVisit TrimRx

MyStart Health vs TrimRx

Complete 2026 Comparison for Weight Loss

Weight Loss

Quick Answer

Best overallTrimRx

TrimRx is our overall pick for weight loss, based on our rating and feature coverage.

Top Weight Loss Providers

Our Top Choice
1
TrimRx logo

GLP-1 Weight Loss From $179/mo - Free 2-Minute Assessment

  • Compounded GLP-1 (semaglutide) from $179/mo, GLP-1 + GIP (tirzepatide) from $259/mo
  • Brand-name Ozempic®, Mounjaro®, Zepbound® and Wegovy® also available
  • Free 2-minute qualification quiz and FREE doctor consultation - no cost, no obligation
  • Free tracked shipping straight to your door after approval
9.4
OutstandingScore based on review by ManyTreatments editors, popularity, brand reputation, features and benefitsLearn how we score
★★★★★
See PricingRead full review
Most Popular
2
Medvi logo

First Month $179, Then $299/mo With No Membership Fee

  • Doctor-guided GLP-1 care, 100% online - no waiting rooms
  • Free dietician visits and care coaching included with your plan
  • Doctor-formulated plans adjusted as your body responds
  • Fast, discreet shipping to your door
9.2
OutstandingScore based on review by ManyTreatments editors, popularity, brand reputation, features and benefitsLearn how we score
★★★★★
See PricingRead full review
Best Value
3
Ro logo

Wegovy® From $149/mo Plus Membership From $74/mo - Free Insurance Check

  • Full GLP-1 suite: Zepbound®, Wegovy® pill and pen, semaglutide and more
  • Free insurance check shows what your plan covers before you pay
  • Tirzepatide (Zepbound®) averaged up to 20.9% body weight loss in the 72-week SURMOUNT-1 trial; individual results vary
  • On-demand provider coaching and support, 100% online
9.3
OutstandingScore based on review by ManyTreatments editors, popularity, brand reputation, features and benefitsLearn how we score
★★★★★
See PricingRead full review

Provider Overview

MyStart Health logo
8.8

Our editorial rating 8.8/10Trustpilot: 4.1/5 from 325 reviews, checked Sep 11, 2026

MyStart Health provides compounded GLP-1 weight loss medications at $299/month with a price lock guarantee. Offers all-inclusive access to clinicians, labs, bloodwork, and shipping with flexible cancellation.

Rating8.8/10
Free ConsultationYes
Free ShippingYes
HSA/FSAYes
Founded2023
HQUnited States

We don't list MyStart Health, and we earn nothing if you choose it.

Read Full Review
TrimRx logo
9.4

Our editorial rating 9.4/10Trustpilot: 3.6/5 from 5,431 reviews, checked Sep 11, 2026

TrimRx is a telehealth weight loss platform offering compounded GLP-1 medications - semaglutide from $149/month and tirzepatide from $249/month - with licensed physician oversight, sourcing through licensed 503A compounding pharmacies, and a money-back guarantee.

Rating9.4/10
Free ConsultationYes
Free ShippingYes
HSA/FSAYes
Founded2020
HQUnited States
Visit TrimRxRead Full Review
VS

Feature Comparison

Feature comparison between MyStart Health and TrimRx
FeatureMyStart HealthMyStart HealthTrimRxTrimRx
Rating8.8/109.4/10
Founded20232020
Free ConsultationYesYes
Free ShippingYesYes
Accepts InsuranceNoNo
HSA/FSA AcceptedYesYes
Mobile AppNoNo
Consultation TypeVideo, AsynchronousAsync (text/questionnaire)
Shipping Time3-5 business days3-5 business days

Pricing Comparison

Pricing comparison between MyStart Health and TrimRx across treatment categories
TreatmentMyStart HealthTrimRx
Weight Loss$299/month$299/month$179/month$179-$249/month

Prices shown are starting costs. Actual pricing varies by treatment plan and medication.

Pros and Cons

MyStart Health

Pros

  • Price lock guarantee at $299/month
  • All-inclusive clinician access
  • Labs and bloodwork included
  • 4-week and 12-week supply options
  • Cancel anytime with full refund policy
  • US-licensed doctors with unlimited support

Cons

  • Does not accept insurance
  • Higher starting price than some competitors
  • Newer company
  • Limited to weight loss only
TrimRx

Pros

  • Lowest price in market at $149/month for semaglutide
  • Money-back guarantee unique in this price range
  • Dispensed through licensed 503A compounding pharmacies
  • 24/7 unlimited support included
  • Can prescribe branded alternatives for insured patients

Cons

  • Weight loss only - no multi-condition coverage
  • Compounded medications are not FDA-approved finished products
  • Does not accept insurance for compounded plans
  • Less brand recognition than Hims or Ro

Which Should You Choose?

MyStart HealthChoose MyStart Health if you:
  • Patients wanting price certainty
  • Those seeking full lab work
  • Patients preferring all-inclusive packages
  • Those valuing unlimited doctor support
Read Our MyStart Health Review
TrimRxChoose TrimRx if you:
  • Patients wanting the lowest monthly GLP-1 cost
  • Those who want a money-back guarantee
  • Patients without insurance who need affordable access
Visit TrimRx

Who This Is For

This is for
  • US adults with a BMI over 27 looking for prescription weight loss medication online.
  • You want to compare medication options, monthly costs, and state availability across multiple telehealth providers.
  • You prefer reviewing licensed provider programs independently before committing to a subscription.
Not for
  • Not suitable if you are pregnant, breastfeeding, or planning to become pregnant soon.
  • If you have a history of eating disorders, online weight loss prescribing is not appropriate for you.
  • If your BMI or health history suggests bariatric surgery, you need an in-person surgical consultation instead.

Frequently Asked Questions

Is MyStart Health or TrimRx better?+

The better choice depends on your specific needs and priorities. MyStart Health carries a 8.8/10 rating in our provider database and is listed as a fit for patients wanting price certainty. TrimRx carries a 9.2/10 rating in our provider database and is listed as a fit for patients wanting the lowest monthly glp-1 cost. Those scores are our own editorial ratings, not third-party review averages. MyStart Health was founded in 2023 in United States, while TrimRx was founded in 2020 in United States. Both are US telehealth platforms that connect you with licensed providers, and which one suits you is a question for that provider.

Which is cheaper, MyStart Health or TrimRx?+

Pricing varies by treatment category. MyStart Health starts at $299/month (range: $299/month). TrimRx starts at $179/month (range: $179-$249/month). These are the rates last recorded in our provider database, so confirm the current price at checkout before you enroll. MyStart Health lists free consultations. TrimRx lists free consultations. MyStart Health lists free shipping. TrimRx lists free shipping. MyStart Health and TrimRx list HSA and FSA payment options, though whether a given charge is eligible depends on your plan and on IRS rules for that expense.

Do MyStart Health and TrimRx accept insurance?+

MyStart Health does not list health insurance as accepted, and operates on a cash-pay model with published pricing. TrimRx does not list insurance as accepted. MyStart Health and TrimRx list HSA and FSA payment options; eligibility for any specific charge depends on your plan and IRS rules, so check with your plan administrator first. Coverage and pricing change, so confirm both with the platform and your insurer before you enroll.

Are MyStart Health and TrimRx legitimate telehealth companies?+

Both are established US telehealth platforms. MyStart Health was founded in 2023 and is headquartered in United States. TrimRx was founded in 2020 in United States. Both state that they work with US-licensed providers and licensed pharmacies and that they operate under HIPAA. We do not independently audit provider credentials or pharmacy licensing, so if you want that confirmed, you can look up an individual prescriber through your state medical board and a pharmacy through your state board of pharmacy.

How do consultations work at MyStart Health vs TrimRx?+

MyStart Health offers video and asynchronous consultations (free). TrimRx provides async (text/questionnaire) consultations (free). On both, you complete a health questionnaire online that a licensed provider reviews. Video consultations are available if you prefer to speak with a provider face to face. Turnaround times vary by platform, by state, and by how busy the provider network is, and you can message your provider with follow-up questions through the platform.

How fast is shipping from MyStart Health and TrimRx?+

MyStart Health lists shipping within 3-5 business days with free standard shipping. TrimRx lists shipping within 3-5 business days with free standard shipping. Both describe discreet packaging, and medications ship from licensed pharmacies rather than from the platform itself. Actual delivery time depends on your state, the pharmacy, and whether your prescription needs follow-up.

Can I cancel MyStart Health or TrimRx subscriptions anytime?+

MyStart Health requires a subscription for most treatments and lists cancellation at any time without a fee. TrimRx also uses a subscription model and lists no cancellation penalty. Cancellation terms are set by each platform and can change, so read the current terms before you enroll. As a general rule you need to cancel before your next billing date to avoid the following period's charge, and anything already shipped is still yours.

Which has better weight loss programs, MyStart Health or TrimRx?+

MyStart Health lists Compounded Semaglutide, Compounded Tirzepatide, Lab Testing starting at $299/month. TrimRx lists Compounded Semaglutide, Compounded Tirzepatide starting at $179/month. Wegovy (semaglutide) and Zepbound (tirzepatide) are the brand-name injectables FDA-approved for weight management. Where a program dispenses compounded semaglutide or tirzepatide instead, that is a pharmacy-prepared drug rather than the approved finished product. Compounded drugs are not FDA-approved and have not been reviewed by the FDA for safety, effectiveness, or quality. Programs typically bundle medication, provider consultations, and check-ins, and they differ mainly on price, on which medications they carry, and on how much support is included. Whether any of this is appropriate for you is a question for a licensed provider.

What are the side effects of treatments from MyStart Health vs TrimRx?+

Side effects come from the medication, not from the platform, so this is mostly a question about the drug you end up on rather than about MyStart Health versus TrimRx. Reported effects vary by treatment: ED medications may cause headache, flushing, or nasal congestion; finasteride carries labeled sexual side effects that some men report persisting after they stop; GLP-1 medications commonly cause nausea, vomiting, and other gastrointestinal effects, especially when the dose goes up; SSRIs may cause drowsiness, nausea, or changes in appetite and sexual function. This is not the full list for any of them. Both platforms have licensed providers review your medical history and screen for contraindications, and you should read the medication guide and raise anything you notice with your provider.

Should I choose MyStart Health or TrimRx?+

Choose MyStart Health if you prioritize: patients wanting price certainty, those seeking full lab work. Choose TrimRx if you prioritize: patients wanting the lowest monthly glp-1 cost, those who want a money-back guarantee. MyStart Health stands out for: Price lock guarantee. TrimRx is known for: Money-back guarantee if you do not lose weight. Both are established telehealth platforms, so your choice mostly comes down to price, which treatments each one carries, and how you prefer to handle visits and refills.

How do I get started with MyStart Health or TrimRx?+

The process is similar on both. For MyStart Health: visit their website, select your treatment category, and complete a health questionnaire that a licensed provider reviews. For TrimRx: follow the same kind of flow on their platform. Both ask for your medical history, current medications, and answers to health screening questions, and being straight with those answers is what lets the provider catch an interaction. If you are approved, the prescription goes to a licensed pharmacy and ships to you (often with free shipping). How long the whole thing takes depends on the platform, your state, and the pharmacy.

How do MyStart Health and TrimRx rate against each other?+

MyStart Health carries a 8.8/10 rating in our provider database, and TrimRx carries a 9.2/10 rating in our provider database. Those are ManyTreatments editorial scores on a 10-point scale, not averages pulled from third-party review sites, and you can read how we build them on our how-we-rate page. What we weigh: MyStart Health scores well on price lock guarantee at $299/month, with does not accept insurance as the trade-off. For TrimRx it is lowest price in market at $149/month for semaglutide, against weight loss only - no multi-condition coverage. If you want customer sentiment as well, check current listings on the review platforms directly, since those move.

Related Comparisons

HimsVSMyStart HealthHimsVSTrimRxHersVSMyStart HealthHersVSTrimRxRoVSMyStart HealthRoVSTrimRx

Start With a Top Weight Loss Provider

Our Top Choice
1
TrimRx logo

GLP-1 Weight Loss From $179/mo - Free 2-Minute Assessment

  • Compounded GLP-1 (semaglutide) from $179/mo, GLP-1 + GIP (tirzepatide) from $259/mo
  • Brand-name Ozempic®, Mounjaro®, Zepbound® and Wegovy® also available
  • Free 2-minute qualification quiz and FREE doctor consultation - no cost, no obligation
  • Free tracked shipping straight to your door after approval
9.4
OutstandingScore based on review by ManyTreatments editors, popularity, brand reputation, features and benefitsLearn how we score
★★★★★
See PricingRead full review
Most Popular
2
Medvi logo

First Month $179, Then $299/mo With No Membership Fee

  • Doctor-guided GLP-1 care, 100% online - no waiting rooms
  • Free dietician visits and care coaching included with your plan
  • Doctor-formulated plans adjusted as your body responds
  • Fast, discreet shipping to your door
9.2
OutstandingScore based on review by ManyTreatments editors, popularity, brand reputation, features and benefitsLearn how we score
★★★★★
See PricingRead full review
Best Value
3
Ro logo

Wegovy® From $149/mo Plus Membership From $74/mo - Free Insurance Check

  • Full GLP-1 suite: Zepbound®, Wegovy® pill and pen, semaglutide and more
  • Free insurance check shows what your plan covers before you pay
  • Tirzepatide (Zepbound®) averaged up to 20.9% body weight loss in the 72-week SURMOUNT-1 trial; individual results vary
  • On-demand provider coaching and support, 100% online
9.3
OutstandingScore based on review by ManyTreatments editors, popularity, brand reputation, features and benefitsLearn how we score
★★★★★
See PricingRead full review

Related Resources

Brand Review

MyStart Health Review

Brand Review

TrimRx Review

Brand Review

Is MyStart Health Legit?

Brand Review

Is TrimRx Legit?

Guide

MyStart Health Alternatives

Guide

TrimRx Alternatives

Eric Gold
Eric GoldEditor-in-Chief

Eric Gold is a writer and editor with a background in digital media and consumer research. He has spent the last several years covering the health and wellness industry, with a particular focus on telehealth services and direct-to-consumer healthcare. Eric believes that access to clear, unbiased information should not require a medical degree. When he is not reviewing telehealth platforms, he enjoys hiking, cooking, and following the stock market a little too closely.

Medical Disclaimer: The information on this page is for educational purposes only and is not medical advice. Always consult with a licensed healthcare provider before starting any treatment. Read our full medical disclaimer.

Regulatory noticeRegulatory note (verified August 22, 2026): On February 20, 2026 the FDA issued MEDVi, LLC a warning letter (MARCS-CMS 721455) citing misbranding under sections 502(a) and 502(bb) of the FD&C Act. Reviewing medvi.io in December 2025, the FDA said labels bearing "MEDVi" implied MEDVi compounds the drugs when it does not, and that "Same active ingredient as Wegovy and Ozempic" and "Same active ingredient as Mounjaro and Zepbound" implied an FDA approval compounded drugs do not have. We found no close-out letter, so the matter appears open. MEDVi states medvi.io is affiliate-operated rather than company-operated; we could not verify that, and the letter is addressed to MEDVi, LLC. Read the FDA letter