PlushCare is a full-service telehealth platform offering virtual urgent care, primary care, and treatment for various conditions including ED, weight loss, and women's health.
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Complete 2026 Comparison for Weight Loss
HealthRx is our overall pick for weight loss, based on our rating and feature coverage.
PlushCare is a full-service telehealth platform offering virtual urgent care, primary care, and treatment for various conditions including ED, weight loss, and women's health.
HealthRx is a physician-supervised GLP-1 weight loss telehealth platform offering compounded semaglutide and tirzepatide from $99/mo, with a 30-day money-back guarantee, no insurance required, and free shipping in 24-48 hours.
| Feature | ||
|---|---|---|
| Rating | 8.6/10 | 9.1/10 |
| Founded | 2014 | 2023 |
| Free Consultation | No | Yes |
| Free Shipping | Yes | Yes |
| Accepts Insurance | Yes | No |
| HSA/FSA Accepted | Yes | Yes |
| Mobile App | Yes | No |
| Consultation Type | Video, Phone | Asynchronous |
| Shipping Time | 3-5 business days | 24-48 hours |
| Treatment | ||
|---|---|---|
| Weight Loss | N/A | $99/month$99-$133/month |
The better choice depends on your specific needs and priorities. PlushCare carries a 8.6/10 rating in our provider database and is listed as a fit for patients with insurance. HealthRx carries a 9.1/10 rating in our provider database and is listed as a fit for those wanting the lowest cash glp-1 price. Those scores are our own editorial ratings, not third-party review averages. PlushCare was founded in 2014 in San Francisco, CA, while HealthRx was founded in 2023 in United States. Both are US telehealth platforms that connect you with licensed providers, and which one suits you is a question for that provider.
Pricing varies by treatment category. PlushCare pricing varies. HealthRx starts at $99/month (range: $99-$133/month). These are the rates last recorded in our provider database, so confirm the current price at checkout before you enroll. HealthRx lists free consultations. PlushCare lists free shipping. HealthRx lists free shipping. PlushCare and HealthRx list HSA and FSA payment options, though whether a given charge is eligible depends on your plan and on IRS rules for that expense.
PlushCare lists health insurance as accepted for some treatments. HealthRx does not list insurance as accepted. PlushCare and HealthRx list HSA and FSA payment options; eligibility for any specific charge depends on your plan and IRS rules, so check with your plan administrator first. Coverage and pricing change, so confirm both with the platform and your insurer before you enroll.
Both are established US telehealth platforms. PlushCare was founded in 2014 and is headquartered in San Francisco, CA. HealthRx was founded in 2023 in United States. Both state that they work with US-licensed providers and licensed pharmacies and that they operate under HIPAA. We do not independently audit provider credentials or pharmacy licensing, so if you want that confirmed, you can look up an individual prescriber through your state medical board and a pharmacy through your state board of pharmacy.
PlushCare offers video and phone consultations. HealthRx provides asynchronous consultations (free). On both, you complete a health questionnaire online that a licensed provider reviews. Video consultations are available if you prefer to speak with a provider face to face. Turnaround times vary by platform, by state, and by how busy the provider network is, and you can message your provider with follow-up questions through the platform.
PlushCare lists shipping within 3-5 business days with free standard shipping. HealthRx lists shipping within 24-48 hours with free standard shipping. Both describe discreet packaging, and medications ship from licensed pharmacies rather than from the platform itself. Actual delivery time depends on your state, the pharmacy, and whether your prescription needs follow-up. You can track your shipment through the provider's mobile app or website.
PlushCare has a mobile app for iOS and Android that you can use to manage prescriptions, message providers, track orders, and see your health information. HealthRx provides a mobile-optimized website for on-the-go access.
PlushCare offers both subscription and one-time purchase options and lists cancellation at any time without a fee. HealthRx also uses a subscription model and lists no cancellation penalty. Cancellation terms are set by each platform and can change, so read the current terms before you enroll. As a general rule you need to cancel before your next billing date to avoid the following period's charge, and anything already shipped is still yours.
PlushCare lists GLP-1 Medications, Weight Management Counseling starting at prices that vary. HealthRx lists Compounded Semaglutide, Compounded Tirzepatide starting at $99/month. Wegovy (semaglutide) and Zepbound (tirzepatide) are the brand-name injectables FDA-approved for weight management. Where a program dispenses compounded semaglutide or tirzepatide instead, that is a pharmacy-prepared drug rather than the approved finished product. Compounded drugs are not FDA-approved and have not been reviewed by the FDA for safety, effectiveness, or quality. Programs typically bundle medication, provider consultations, and check-ins, and they differ mainly on price, on which medications they carry, and on how much support is included. Whether any of this is appropriate for you is a question for a licensed provider.
Side effects come from the medication, not from the platform, so this is mostly a question about the drug you end up on rather than about PlushCare versus HealthRx. Reported effects vary by treatment: ED medications may cause headache, flushing, or nasal congestion; finasteride carries labeled sexual side effects that some men report persisting after they stop; GLP-1 medications commonly cause nausea, vomiting, and other gastrointestinal effects, especially when the dose goes up; SSRIs may cause drowsiness, nausea, or changes in appetite and sexual function. This is not the full list for any of them. Both platforms have licensed providers review your medical history and screen for contraindications, and you should read the medication guide and raise anything you notice with your provider.
Choose PlushCare if you prioritize: patients with insurance, those wanting video consultations. Choose HealthRx if you prioritize: those wanting the lowest cash glp-1 price, people without glp-1 insurance coverage. PlushCare stands out for: Full primary care telehealth. HealthRx is known for: Cash price from $99/mo on the 12-month plan. Both are established telehealth platforms, so your choice mostly comes down to price, which treatments each one carries, and how you prefer to handle visits and refills.
The process is similar on both. For PlushCare: visit their website, select your treatment category, and complete a health questionnaire that a licensed provider reviews. For HealthRx: follow the same kind of flow on their platform. Both ask for your medical history, current medications, and answers to health screening questions, and being straight with those answers is what lets the provider catch an interaction. If you are approved, the prescription goes to a licensed pharmacy and ships to you (often with free shipping). How long the whole thing takes depends on the platform, your state, and the pharmacy.
PlushCare carries a 8.6/10 rating in our provider database, and HealthRx carries a 9.1/10 rating in our provider database. Those are ManyTreatments editorial scores on a 10-point scale, not averages pulled from third-party review sites, and you can read how we build them on our how-we-rate page. What we weigh: PlushCare scores well on accepts most major insurance plans, with consultation fee ($99 without insurance) as the trade-off. For HealthRx it is compounded semaglutide from $99/mo on the 12-month plan, against $99/mo requires the 12-month plan; 3-month is $133/mo. If you want customer sentiment as well, check current listings on the review platforms directly, since those move.
Medical Disclaimer: The information on this page is for educational purposes only and is not medical advice. Always consult with a licensed healthcare provider before starting any treatment. Read our full medical disclaimer.
Verification limitationVerification note (checked August 23, 2026): we could not identify the legal entity behind HealthRx through public records. Its website does not name an operating company, its domain registration is privacy-shielded, and we could not confirm a listing in any business registry or accreditation database we checked. This is not a finding of wrongdoing. It means our usual checks, including our search of FDA enforcement records, could only be run against the brand name and domain rather than a confirmed company.
Regulatory noticeRegulatory note (verified August 22, 2026): On February 20, 2026 the FDA issued MEDVi, LLC a warning letter (MARCS-CMS 721455) citing misbranding under sections 502(a) and 502(bb) of the FD&C Act. Reviewing medvi.io in December 2025, the FDA said labels bearing "MEDVi" implied MEDVi compounds the drugs when it does not, and that "Same active ingredient as Wegovy and Ozempic" and "Same active ingredient as Mounjaro and Zepbound" implied an FDA approval compounded drugs do not have. We found no close-out letter, so the matter appears open. MEDVi states medvi.io is affiliate-operated rather than company-operated; we could not verify that, and the letter is addressed to MEDVi, LLC. Read the FDA letter