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Content is for informational purposes only and is not medical advice. Compounded medications are not FDA-approved for safety, effectiveness, or quality. Medical Disclaimer

  1. Home
  2. Compare
  3. PlushCare vs TrimRx
Eric GoldWritten by Eric GoldEditor-in-Chief
PlushCare telehealth platform
PlushCare
VS
TrimRx telehealth platform
TrimRx
Visit PlushCareVisit TrimRx

PlushCare vs TrimRx

Complete 2026 Comparison for Weight Loss

Weight Loss

Quick Answer

Best overallTrimRx
Most reviewedTrimRx

TrimRx is our overall pick for weight loss, based on ratings, reviews, and feature coverage.

Provider Overview

PlushCare logo
8.6(2,600 reviews on Trustpilot)

PlushCare is a full-service telehealth platform offering virtual urgent care, primary care, and treatment for various conditions including ED, weight loss, and women's health.

Rating8.6/10
Reviews2,600
Free ShippingYes
HSA/FSAYes
Founded2014
HQSan Francisco, CA
Visit PlushCareRead Full Review
TrimRx logo
9.2(350,000 reviews on TrimRx.com (self-reported))

TrimRx is a telehealth weight loss platform offering compounded GLP-1 medications - semaglutide from $149/month and tirzepatide from $249/month - with licensed physician oversight, FDA-registered 503B pharmacy sourcing, and a money-back guarantee.

Rating9.2/10
Reviews350,000
Free ShippingYes
HSA/FSAYes
Founded2020
HQUnited States
Visit TrimRxRead Full Review
VS

Feature Comparison

Feature comparison between PlushCare and TrimRx
FeaturePlushCareTrimRx
Rating8.6/59.2/5
Reviews2,600350,000
Founded20142020
Free ConsultationNoYes
Free ShippingYesYes
Accepts InsuranceYesNo
HSA/FSA AcceptedYesYes
Mobile AppYesNo
Consultation TypeVideo, PhoneAsync (text/questionnaire)
Shipping Time3-5 business days3-5 business days

Pricing Comparison

Pricing comparison between PlushCare and TrimRx across treatment categories
TreatmentPlushCareTrimRx
Weight Loss$189/month$189-$450/month$149/mo$149-$249/mo

Prices shown are starting costs. Actual pricing varies by treatment plan and medication.

Pros and Cons

PlushCare

Pros

  • Accepts most major insurance plans
  • Primary care and urgent care available
  • Board-certified physicians only
  • Same-day appointments often available
  • full-service care options

Cons

  • Consultation fee ($99 without insurance)
  • More expensive than specialists
  • Requires appointments
  • Not specialized in any single condition
TrimRx

Pros

  • Lowest price in market at $149/month for semaglutide
  • Money-back guarantee unique in this price range
  • 350,000+ patient track record
  • FDA-registered 503B pharmacy sourcing
  • 24/7 unlimited support included
  • Can prescribe branded alternatives for insured patients

Cons

  • Weight loss only - no multi-condition coverage
  • Compounded medications are not FDA-approved finished products
  • Does not accept insurance for compounded plans
  • Less brand recognition than Hims or Ro

Which Should You Choose?

PlushCareChoose PlushCare if you:
  • Patients with insurance
  • Those wanting video consultations
  • Patients needing full primary care
  • Those seeking same-day appointments
Visit PlushCare
TrimRxChoose TrimRx if you:
  • Patients wanting the lowest monthly GLP-1 cost
  • Those who want a money-back guarantee
  • Patients without insurance who need affordable access
Visit TrimRx

Who This Is For

This is for
  • US adults with a BMI over 27 looking for prescription weight loss medication online.
  • You want to compare medication options, monthly costs, and state availability across multiple telehealth providers.
  • You prefer reviewing licensed provider programs independently before committing to a subscription.
Not for
  • Not suitable if you are pregnant, breastfeeding, or planning to become pregnant soon.
  • If you have a history of eating disorders, online weight loss prescribing is not appropriate for you.
  • If your BMI or health history suggests bariatric surgery, you need an in-person surgical consultation instead.

Frequently Asked Questions

Is PlushCare or TrimRx better?+

The better choice depends on your specific needs and priorities. PlushCare (rated 8.6/5 from 2,600 reviews) is best for patients with insurance. TrimRx (rated 9.2/5 from 350,000 reviews) excels at patients wanting the lowest monthly glp-1 cost. PlushCare was founded in 2014 in San Francisco, CA, while TrimRx was founded in 2020 in United States. Both are legitimate, licensed telehealth providers with board-certified physicians.

Which is cheaper, PlushCare or TrimRx?+

Pricing varies by treatment category. PlushCare starts at $189/month (range: $189-$450/month). TrimRx starts at $149/mo (range: $149-$249/mo). TrimRx offers free consultations. PlushCare provides free shipping. TrimRx provides free shipping. Both platforms accept HSA/FSA payments for eligible treatments.

Do PlushCare and TrimRx accept insurance?+

PlushCare accepts health insurance for some treatments, which can reduce considerably your out-of-pocket costs. TrimRx does not accept insurance. Both platforms accept HSA (Health Savings Account) and FSA (Flexible Spending Account) payments for eligible medical expenses.

Are PlushCare and TrimRx legitimate telehealth companies?+

Yes, both PlushCare and TrimRx are legitimate, licensed telehealth platforms. PlushCare was founded in 2014 and is headquartered in San Francisco, CA. TrimRx was founded in 2020 in United States. Both employ board-certified physicians licensed in your state, follow HIPAA regulations for patient privacy, and partner with licensed pharmacies to fulfill prescriptions. You can verify their credentials through state medical boards and pharmacy licensing authorities.

How do consultations work at PlushCare vs TrimRx?+

PlushCare offers video and phone consultations. TrimRx provides async (text/questionnaire) consultations (free). Both platforms allow you to complete a health questionnaire online, which is reviewed by a licensed healthcare provider. Video consultations are available for patients who prefer face-to-face interaction with their provider. Response times are typically within 24-48 hours, and you can message your provider with follow-up questions through the platform.

How fast is shipping from PlushCare and TrimRx?+

PlushCare ships within 3-5 business days with free standard shipping. TrimRx ships within 3-5 business days with free standard shipping. Both platforms use discreet packaging with no indication of the contents. Medications are shipped directly from licensed pharmacies to your door. You can track your shipment through the provider's mobile app or website.

Do PlushCare and TrimRx have mobile apps?+

PlushCare has a mobile app available for iOS and Android, allowing you to manage prescriptions, message providers, track orders, and access your health information. TrimRx provides a mobile-optimized website for on-the-go access.

Can I cancel PlushCare or TrimRx subscriptions anytime?+

PlushCare offers both subscription and one-time purchase options and allows you to cancel anytime without fees. TrimRx also uses a subscription model with no cancellation penalties. Both platforms allow you to pause, modify, or cancel your subscription through your online account. Note that you should cancel before your next billing date to avoid being charged for the following period. Any medications already shipped will still be delivered.

Which has better weight loss programs, PlushCare or TrimRx?+

Both offer GLP-1 weight loss medications. PlushCare provides GLP-1 Medications, Weight Management Counseling starting at $189/month. TrimRx offers Compounded Semaglutide, Compounded Tirzepatide starting at $149/mo. Both platforms offer compounded semaglutide, which is the same active ingredient as Ozempic and Wegovy. Clinical studies show GLP-1 medications can help patients lose 15-20% of body weight. Programs typically include medication, provider consultations, and ongoing support. Results vary based on adherence, diet, and lifestyle factors.

What are the side effects of treatments from PlushCare vs TrimRx?+

Side effects depend on the medication, not the platform, since both PlushCare and TrimRx prescribe the same FDA-approved medications. Common side effects vary by treatment: ED medications may cause headaches, flushing, or nasal congestion; finasteride for hair loss may affect libido in 1-2% of users; GLP-1 weight loss medications commonly cause nausea, especially initially; SSRIs for mental health may cause drowsiness or changes in appetite. Both platforms have licensed physicians who review your medical history to ensure treatments are safe for you and monitor for any adverse effects.

Should I choose PlushCare or TrimRx?+

Choose PlushCare if you prioritize: patients with insurance, those wanting video consultations. Choose TrimRx if you prioritize: patients wanting the lowest monthly glp-1 cost, those who want a money-back guarantee. PlushCare stands out for: Full primary care telehealth. TrimRx is known for: Money-back guarantee if you do not lose weight. Both are reputable telehealth providers - your choice may come down to pricing, specific treatment options, or user experience preferences.

How do I get started with PlushCare or TrimRx?+

Getting started with either platform is straightforward. For PlushCare: Visit their website, select your treatment category, complete a health questionnaire, and a licensed provider will review your information within 24-48 hours. For TrimRx: Follow a similar process on their platform. Both require you to provide your medical history, current medications, and answer health screening questions. If approved, your prescription is sent to a licensed pharmacy and shipped to your door (often with free shipping). The entire process from signup to receiving medication typically takes 3-7 days.

What do customers say about PlushCare vs TrimRx?+

PlushCare has a 8.6/5 rating from 2,600 reviews on Trustpilot. Customers praise: accepts most major insurance plans. Common complaints include: consultation fee ($99 without insurance). TrimRx has a 9.2/5 rating from 350,000 reviews on TrimRx.com (self-reported). Customers appreciate: lowest price in market at $149/month for semaglutide. Some note: weight loss only - no multi-condition coverage. Both platforms have the positive reviews typical of established telehealth providers and responsive customer service teams.

Related Comparisons

HimsVSPlushCareHimsVSTrimRxHersVSPlushCareHersVSTrimRxRoVSPlushCareRoVSTrimRx

Related Resources

Brand Review

PlushCare Review

Brand Review

TrimRx Review

Brand Review

Is PlushCare Legit?

Brand Review

Is TrimRx Legit?

Guide

PlushCare Alternatives

Guide

TrimRx Alternatives

Eric Gold
Eric GoldEditor-in-Chief

Eric Gold is a writer and editor with a background in digital media and consumer research. He has spent the last several years covering the health and wellness industry, with a particular focus on telehealth services and direct-to-consumer healthcare. Eric believes that access to clear, unbiased information should not require a medical degree. When he is not reviewing telehealth platforms, he enjoys hiking, cooking, and following the stock market a little too closely.

Medical Disclaimer: The information on this page is for educational purposes only and is not medical advice. Always consult with a licensed healthcare provider before starting any treatment. Read our full medical disclaimer.