You have more telehealth weight loss options today than you can reasonably compare on your own. So we did the comparing: here are our top 10, each with our own editorial rating, not a generic roundup. Flat starting prices in this top 10 run from $99/mo at Strut and HealthRx up to $199/mo at Sprout Health. Three entries are not flat, and the difference is large enough to reorder the list: Sesame Care's $59/mo covers visits and care only; Hers quotes medication only, with a separate Hers Weight Loss Membership required at $39 for the first month and $149/mo after that; and Medvi's $179 covers your first month only, with refills at $299/mo. Add the two Hers charges together and Hers runs about $298/mo ongoing rather than the $149 to $199 its medication prices suggest, and Medvi sits just above it at $299/mo once that first month ends, so the two highest ongoing prices in this top 10 both hide behind a cheaper-looking headline. Hims is not ranked here, but it runs the identical membership structure to Hers at the identical figures, so those two sit level at $298 rather than either one being uniquely costly. So read every figure below for what it does and does not include before you rank them against each other. Each rating is our team's own 1-10 editorial assessment, and the order those ratings sit in is a position we set by hand rather than a sort, which the How We Rank This List section below spells out in full. Every price is the provider's own starting figure, last verified against live pricing in August 2026, with the Hers, Sesame Care, Ro, and Fridays figures rechecked in September 2026. Where a program leans on compounded medication (not FDA-approved, not reviewed by the FDA for safety, effectiveness, or quality), that's called out explicitly rather than left implied.
Step 1: Decide What Matters Most to You: Price, Speed, or Medication Choice
Before you look at rank order, decide which factor actually drives your decision, because the #1-rated program on this list isn't automatically the right one for you. If price is your priority, the lowest flat starting prices in our top 10 are Strut and HealthRx at $99/mo (HealthRx's on a 12-month plan), with Sesame Care's $59/mo covering visits and care while medication is billed separately. If you specifically want an FDA-approved brand-name medication rather than a compounded one, that narrows the list further.
- Budget-first: check Strut and HealthRx first, both with flat starting prices of $99/mo, then Fridays at $150/mo on its annual plan
- Brand-name-first: Ro, Hers, and TrimRx are the three that explicitly list FDA-approved brand options in their features
- Speed-first: shipping timelines differ program to program; check the specific brand's page for its stated turnaround
Step 2: Compare Compounded vs Brand-Name Access Across the List
Seven of our top 10 lead with
compounded semaglutide or tirzepatide, which is not FDA-approved and not reviewed by the FDA for safety, effectiveness, or quality, prepared by a licensed pharmacy instead of the brand manufacturer: TrimRx, Shed, Fridays, Strut, Sprout Health, HealthRx, and Medvi, whose featured plan runs on compounded GLP-1 medication from pharmacy partners it names on its own site at $179 for your first month and $299/mo after that. The other three (Ro, Sesame Care, Hers) frame their offering around brand-name or insurance-checked medication instead. Medvi separately runs a brand-name Wegovy/Zepbound track priced at membership plus medication cost rather than a flat rate, if you want FDA-approved product from that same provider. Neither approach is automatically better; it changes your price and what regulatory review has (or hasn't) touched your specific medication.
- The lowest flat starting prices on this list (Strut and HealthRx at $99/mo, Fridays at $150/mo on an annual plan) are all compounded-forward programs
- Brand-name-forward programs (Ro, Hers) tend to route through an insurance check first
- Ask directly which category your quoted price falls into before you sign up
Step 3: Confirm State Availability and Shipping Before You Sign Up
Not every program on this list ships to or operates in every state, and requirements can differ by medication type within the same company. Confirm your state is covered and ask about shipping timeline and packaging (most compounded-medication providers ship in temperature-controlled packaging) before you complete an intake form, not after.
- State availability varies by provider and sometimes by specific medication
- Injectable medications generally require cold-chain shipping; oral options don't
- A program's own brand page on this site lists its current features and starting price
Step 4: Complete the Intake Quiz for Your Top-Ranked Match
Once you've narrowed the list using price, medication type, and state availability, complete that provider's online health quiz. A licensed provider reviews it and confirms whether you're a fit before anything ships. This step is the same across every program on this list, regardless of rank.
- Have your health history and current medications ready so the review isn't delayed
- A real medical review, not a checkbox form, is what separates a legitimate program from one to avoid
- You're not committed to a program until a licensed provider approves you and you complete checkout
How We Put This List Together
Every provider here carries a 1-10 rating from our team. That rating is an editorial assessment, not a computed or weighted score, and there is no formula behind it. What informs it is set out in full on our
How We Rate page: what a provider charges, which medications it offers and whether those are FDA-approved, how many states it covers, and what the company publishes about its own service. The rating you see beside each entry below is the same one that appears on that brand's own page here.
Each rating is published with a label: 9.5-10.0 Exceptional, 9.2-9.4 Outstanding, 9.0-9.1 Excellent, 8.0-8.9 Very Good. Across these 10 providers, five sit in the Outstanding band and five in Excellent, and none rates below 9.0. Two things worth stating plainly. The order below is not a strict ranking by rating: several of these providers are tied, and Strut at 9.4 rates above several listed ahead of it. That order is a position number we set by hand for each provider in this category, so nothing here is calculated when the page loads and nothing is sorted by rating. And most of the providers here pay us a commission when you buy through our links. We accept no payment for placement, no payment for a rating, and no listing fees, so nobody bought a spot on this list, but we are not going to tell you the order is independent of what we earn either, because we cannot show you a rule that keeps our revenue out of it. Read the list with that in view and compare on the price, rating, and FDA approval status stated in each entry.
1. TrimRx: 9.4/10, Outstanding
TrimRx rates 9.4/10 (Outstanding), tied with Strut for the highest rating on this list. Compounded semaglutide starts at $179/mo and compounded tirzepatide (GLP-1 + GIP) starts at $259/mo; compounded medications are not FDA-approved and are not reviewed by the FDA for safety, effectiveness, or quality. Brand-name Ozempic, Mounjaro, Zepbound, and Wegovy are also available if you'd rather stay on an FDA-approved product. The qualification quiz and doctor consultation are both free with no obligation, and shipping is free and tracked.
Honest tradeoff: this is not the budget pick. At $179/mo, TrimRx costs more to start than half of our top 10, and the tirzepatide option runs $259/mo, among the higher prices here. What you're paying for is one of the two highest ratings here and the widest medication selection (both compounded and all four brand names), not the lowest bill.
2. Ro: 9.3/10, Outstanding
Ro rates 9.3/10 (Outstanding). It offers the full GLP-1 suite, Zepbound, Wegovy (both pill and pen), and more, with medication from $149/mo as of September 2026 (the Wegovy or Foundayo pill; the Wegovy pen is $199/mo and the Zepbound KwikPen $299/mo), and it runs a free insurance check up front to show what your plan actually covers before you pay anything.
Honest tradeoff: Ro bills the medication and a Ro Body membership as two separate line items, so neither number alone is your monthly cost. The membership is $39 for the first month, then $74-$149/mo depending on how long a term you commit to, with $74 being the annual-prepay rate. Add the cheapest of each and the honest ongoing floor is about $223/mo, which puts Ro in the upper half of this list rather than the lower half. Pin down both of your own figures, and what the insurance check turns up, before you stack Ro against the flat monthly prices here.
3. Medvi: 9.2/10, Outstanding
Medvi rates 9.2/10 with doctor-guided GLP-1 care at $299/mo ongoing, with your first month at $179. That plan is compounded semaglutide or tirzepatide, produced by pharmacy partners Medvi names on its own site; compounded medications are not FDA-approved and are not reviewed by the FDA for safety, effectiveness, or quality. Free dietician visits and care coaching are included, and doctor-formulated plans adjust as your body responds to treatment. Medvi also runs a separate brand-name Wegovy/Zepbound track priced at membership plus medication cost, not a flat total.
Honest tradeoff: the $179 buys you one month. From your first refill on you pay $299/mo, the highest ongoing compounded price in this top 10, while TrimRx holds $179/mo every month at a higher rating. And unlike TrimRx's price-by-medication breakdown, Medvi's figures cover only its compounded tier; its brand-name track has no published flat price. Confirm which tier, which medication, and which month your quote covers before you sign up.
4. Shed: 9.0/10, Excellent
Shed rates 9.0/10 (Excellent). Compounded semaglutide starts at $159/mo on a 12-month term and compounded tirzepatide from $239/mo; compounded medications are not FDA-approved and are not reviewed by the FDA for safety, effectiveness, or quality. Shed backs its program with a published 120-day guarantee (a refund policy, not a promised weight result), and checkout and your visit both happen entirely online.
Honest tradeoff: nothing else in our top 10 publishes a time-boxed refund guarantee like that, and it's a real differentiator. Just don't call Shed cheap: the $159/mo start requires a 12-month commitment, and Strut, HealthRx, Fridays, and Ro all start lower.
5. Sesame Care: 9.1/10, Excellent
Sesame Care rates 9.1/10 (Excellent). Ongoing video visits, a dedicated provider, labs, and messaging start at $59/mo, with cash-pay GLP-1 medication itself listed separately starting around $149/mo (insurance is also accepted for weight-loss medication where your plan allows it). Sesame reports more than 1 million treated to date and 95% satisfaction.
Honest tradeoff: like Ro, the $59/mo headline covers the visit and care access, not the medication, so it is never your full monthly total. Read both halves of the price as a ladder rather than a flat rate. As of September 2026 Sesame lists the care plan from $59/mo on an annual subscription and $99/mo month to month, and it lists the oral Wegovy pill at $149/mo at the lower 1.5mg and 4mg doses, rising to $299/mo at the 9mg and 25mg maintenance doses. The Wegovy and Ozempic pens are listed at $199/mo for the first two months for new starts, then $349/mo. Budget on the dose you expect to settle at, not on the number you pay in month one.
6. Hers: 9.1/10, Excellent
Hers rates 9.1/10 (Excellent). Injectable semaglutide starts at $199/mo, with oral GLP-1 options from $149/mo, and Hers describes its lineup as including name-brand, FDA-approved options with no price markups. Read those figures as medication only. Hers states on its weight-loss pricing (checked September 2026) that the price covers medication if prescribed and that an active Hers Weight Loss Membership is required, billed separately at $39 for the first month and auto-renewing at $149/mo after that.
Honest tradeoff: the membership is not a perk bundled into the price, it is a second charge about the size of the first. Once the introductory month ends, the oral option runs about $298/mo all in and the injectable about $348/mo, which puts Hers at the expensive end of this top 10, level with Medvi's $299/mo ongoing on the oral option and above it on the injectable, rather than in the middle where its headline figures place it. Hims prices the same way and lands at the same $298, so treat the two as one tier and not as a cheap option either of them offers. The $149/mo figure also applies to the oral options specifically, so check that the quote you are given matches both the medication form you want and the membership you will be renewing.
7. Fridays: 9.2/10, Outstanding
Fridays lands at 9.2/10. As of September 2026, compounded semaglutide starts at $150/mo on the annual plan, or $249/mo if you pay month to month, and compounded tirzepatide from $198/mo; compounded medications are not FDA-approved and are not reviewed by the FDA for safety, effectiveness, or quality. Fridays also offers an insurance concierge to try to maximize coverage and a GLP-1 microdosing option.
Honest tradeoff: the $150/mo entry price is an annual-commitment rate. Pay month to month and the same compounded semaglutide is $249/mo, which is a $99 swing for the flexibility to stop. Decide which of those two you are actually buying before you compare Fridays with the flat prices elsewhere on this list. So why #7? Its published feature list is shorter and less specific than TrimRx's or Shed's, and the rating just below the top three reflects that.
8. Strut: 9.4/10, Outstanding
Strut rates 9.4/10, tied for the highest rating on this list, with compounded injectable semaglutide starting at $99/mo, prescribed by U.S.-licensed physicians; compounded medication is not FDA-approved and is not reviewed by the FDA for safety, effectiveness, or quality. The online MD visit and follow-up care are free, and you can fill through Strut's pharmacy network or your own local pharmacy.
Honest tradeoff: $99/mo is one of the lowest prices in our top 10, but nowhere in Strut's published features will you find a brand-name option. If FDA-approved Ozempic, Wegovy, Mounjaro, or Zepbound is what you want, look at TrimRx, Ro, or Hers instead.
9. Sprout Health: 9.0/10, Excellent
Sprout Health rates 9.0/10 (Excellent). Compounded semaglutide and tirzepatide programs start at $199/mo; compounded medications are not FDA-approved and are not reviewed by the FDA for safety, effectiveness, or quality. Medication ships from a US pharmacy in discreet, refrigerated packaging, with dosing personalized by US-licensed clinicians.
Honest tradeoff: Sprout's own materials cite an average 6.4% self-reported body weight loss in the first 12 weeks among its members (individual results vary). That's a company-reported figure from its own user base, not an independent clinical trial result like the 14.9%-20.9% figures from the named GLP-1 trials covered in our
weight loss injections guide; treat the two kinds of numbers differently when you compare them.
10. HealthRx: 9.1/10, Excellent
HealthRx rates 9.1/10 and rounds out our top 10. Compounded semaglutide and tirzepatide start at $99/mo on a 12-month plan ($133/mo if you choose the 3-month plan instead); compounded medication is not FDA-approved and is not reviewed by the FDA for safety, effectiveness, or quality. HealthRx offers a full refund if a licensed provider doesn't approve you. Medication ships from US pharmacies within 24 to 48 hours.
Honest tradeoff: $99/mo matches Strut for the lowest published price in our top 10, but read the fine print: that's the 12-month plan. The shorter 3-month commitment runs $133/mo. Know which term you're actually signing up for before you weigh the $99 figure against other programs' month-to-month pricing.
Compare the Full List and Get Started
The order you just read is ours and we set it by hand: a position number our team assigns each provider in this category, with the 1-10 rating beside it an editorial judgment rather than a formula, which is why Strut at 9.4 sits at #8 and why rank here is a starting point rather than a verdict. That is also why Step 1 asked you to fix your own priority first: price, brand-name access, and speed will not always point at the same program our order does. Once you have settled on one, its entry above already gives you what you need before checkout: whether the price you were quoted covers compounded or brand-name medication, whether it covers one month or every month, and whether a named pharmacy and an individual provider review stand behind it instead of an automated form.
Online vs In-Person Treatment Comparison
Understanding the differences between online and in-person treatment helps you choose the right approach for your needs.
| Feature | Widest Medication Lineup: TrimRx (9.4/10) | Lowest Flat Price in Top 10: HealthRx / Strut ($99/mo) |
|---|
| Starting price | $179/mo (compounded semaglutide), $259/mo (compounded tirzepatide) | $99/mo (HealthRx 12-mo plan or Strut, both compounded semaglutide) |
| Overall rating | 9.4/10, Outstanding | 9.1/10, Excellent (HealthRx); 9.4/10, Outstanding (Strut) |
| Medication options | Compounded semaglutide and tirzepatide, plus brand-name Ozempic, Mounjaro, Zepbound, and Wegovy | Compounded semaglutide and tirzepatide only (HealthRx); compounded semaglutide only (Strut); no brand-name option listed |
| Approval process | Free 2-minute quiz and free doctor consultation, no obligation | Full refund if a licensed provider doesn't approve you (HealthRx); free MD visit and follow-up (Strut) |
| Shipping | Free, tracked shipping | 24-48 hours from US pharmacies (HealthRx); Strut's pharmacy network or your local pharmacy (Strut) |
Frequently Asked Questions
What is the best telehealth weight loss program?
In our editorial ratings, TrimRx and Strut share the highest rating on this list at 9.4/10 (Outstanding). TrimRx offers both compounded and brand-name GLP-1 medications starting at $179/mo; Strut's compounded semaglutide starts at $99/mo. "Best" depends on what you're optimizing for, though: Strut and HealthRx tie for the lowest flat compounded-medication price in our top 10 at $99/mo, and Sesame Care's visits-and-care fee starts lower at $59/mo, with medication billed separately.
What is the cheapest telehealth weight loss program?
Among our top 10 rated programs, Sesame Care has the lowest headline figure at $59/mo, though that covers video visits, a dedicated provider, labs, and messaging, with cash-pay GLP-1 medication billed separately from around $149/mo. Both halves of that move with the terms you pick: as of September 2026 Sesame lists $59/mo on an annual subscription and $99/mo month to month, and the $149/mo medication figure is the oral Wegovy pill at its lower 1.5mg and 4mg doses, listed at $299/mo once you reach the 9mg or 25mg maintenance doses. So the cheapest entry point and the cheapest steady state are not the same program. For a flat compounded-medication starting price, Strut and HealthRx are both $99/mo (HealthRx's $99/mo specifically applies to its 12-month plan; its 3-month plan is $133/mo).
How do you rank these telehealth weight loss programs?
This list uses our own provider ratings, described in full on our How We Rate page. Each one is a 1-10 editorial assessment made by our team rather than a computed or weighted score, informed by what a provider charges, which medications it offers and their FDA-approval status, how many states it covers, and what the company publishes about its service. The order of the list is not a strict ranking by rating. It is a position number we set by hand for each provider, not a calculation run when the page loads. No provider pays us for a position, a rating, or a listing, and we also do not claim the order is independent of what we earn, so compare on the prices and ratings beside each entry rather than on where it sits.
Is compounded semaglutide from these programs safe?
Compounded semaglutide and tirzepatide, offered by 7 of the 10 programs in this ranking, are not FDA-approved and are not reviewed by the FDA for safety, effectiveness, or quality; they're prepared by a licensed compounding pharmacy rather than manufactured by the original drugmaker, and they haven't gone through the FDA review process the brand-name drugs did. You don't have to take that on faith with any program ranked here: each entry above states specifically whether it leads with compounded or brand-name medication, and where a program is cash-pay compounded, its entry names the starting price, the plan term that price depends on, and where the medication ships from, which is the kind of detail you can hold a program to at checkout.
Can I use insurance with these telehealth weight loss programs?
It varies by program. Ro runs a free insurance check up front to show what your plan covers before you pay, and Sesame Care accepts insurance for weight-loss medication where your plan allows it. Programs leading with compounded medication (TrimRx, Shed, Fridays, Strut, Sprout Health, HealthRx, Medvi) are generally cash-pay, since compounded products aren't FDA-approved and typically fall outside insurance formularies.
What's the difference between this list and your weight loss injections guide?
Our weight loss injections guide explains the medications themselves, semaglutide, tirzepatide, and liraglutide, their clinical trial results, and how the injection process works. This page covers the actual telehealth companies you'd sign up with, with our editorial rating on each, so you can compare specific providers by price and what's included rather than by drug type.
Editorial Note: Researched and edited by our editorial team. AI tools assist with initial research and drafting; all content is fact-checked and edited by humans before publication. Learn more about our editorial standards
