GLP-1 Price Index 2026
Real monthly pricing for semaglutide and tirzepatide weight-loss programs across every provider we track, updated continuously. Last refreshed September 2026.
Key Takeaways
As of May 2026, GLP-1 weight-loss programs across the 14 providers in the ManyTreatments Price Index range from $99 per month (Strut) to $299 per month (Medvi), with a median starting price of $189 per month. For comparison, branded self-pay semaglutide (Wegovy) runs $349-$399 per month through NovoCare (as low as $199 with the introductory rate through December 31, 2026), and branded tirzepatide (Zepbound) runs $299-$449 through LillyDirect vials with an on-time refill within 45 days (up to $699 if a refill lapses). The published retail list prices for both sit above $1,000 per month, but that is a sticker figure rather than a current cash-pay price: the manufacturer self-pay channels above are what you pay without insurance. Branded figures as of August 2026; confirm current pricing at checkout.
Provider Price Table
Starting prices for GLP-1 weight-loss programs, sorted low to high. Figures reflect the lowest advertised entry price for each provider and are refreshed from our tracking data. Prices often rise with dose escalation, so treat these as entry points, not maintenance costs.
| Rank | Provider | Starting Price | Billing |
|---|---|---|---|
| 1 | Strut | $99.00 | per month |
| 2 | HealthRx | $99.00 | per month |
| 3 | Eden | $129.00 | per month |
| 4 | Skinny.Rx | $149.25 | per month |
| 5 | Fridays | $150.00 | per month |
| 6 | Shed | $159.00 | per month |
| 7 | TrimRx | $179.00 | per month |
| 8 | Sprout Health | $199.00 | per month |
| 9 | Sesame Care | $208.00 | per month |
| 10 | Peter MD | $209.00 | per month |
| 11 | Ro | $223.00 | per month |
| 12 | Hers | $298.00 | per month |
| 13 | Hims | $298.00 | per month |
| 14 | Medvi | $299.00 | per month |
Self-Pay Price Benchmarks
Reference prices for the branded products through manufacturer and retail channels, plus the compounded telehealth band, for comparison against the program prices above. The branded products are FDA-approved; compounded semaglutide is not, and is not reviewed by the FDA for safety, effectiveness, or quality.
| Product / Channel | Price | Channel | Notes |
|---|---|---|---|
| Compounded semaglutide (telehealth programs) | $99-$299/month | Telehealth | Individually prescribed compounded formulations; $99 is the cheapest program in our weight-loss rankings, $299 the highest ongoing price among them. Not FDA-approved and not reviewed by the FDA for safety, effectiveness, or quality |
| Wegovy (semaglutide) | $349-$399/month | Manufacturer direct | NovoCare Pharmacy self-pay ($199/mo intro through Dec 31, 2026); as of August 2026, confirm at checkout |
| Zepbound (tirzepatide) vials | $299-$449/month | Manufacturer direct | LillyDirect self-pay with on-time refill within 45 days (up to $699 if it lapses); as of August 2026, confirm at checkout |
| Wegovy retail list | ~$1,350/month | Retail | Published list price, not the NovoCare self-pay price above |
| Zepbound retail list | ~$1,086/month | Retail | Published list price, not the LillyDirect self-pay price above |
How We Track These Prices
The ManyTreatments GLP-1 Price Index reflects the lowest advertised starting price for each weight-loss provider we actively track, pulled from our own provider database and refreshed continuously. We include both compounded semaglutide programs and branded product access where providers offer it.
Two limits keep this honest. First, starting prices understate real cost, because standard dose escalation raises what you pay within a few months, and some programs bill lab work or follow-up visits separately. Second, the index tracks advertised entry pricing, not negotiated insurance rates, which can bring your cost as low as $25 per month with a manufacturer savings card if you are covered. Branded benchmark prices come from manufacturer self-pay channels (NovoCare, LillyDirect) and published retail list prices, verified against the sources on our compounded semaglutide cost guide and Zepbound cost guide.
Related Resources
Pricing Disclaimer: Prices reflect advertised starting rates tracked by ManyTreatments and are provided for informational comparison only. Actual costs depend on dose, plan, and included services, and change frequently. Verify current pricing directly with each provider before purchasing. This is not medical advice; consult a licensed provider before starting any medication.