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  1. Home
  2. Compare
  3. Sesame Care vs TrimRx
Eric GoldWritten by Eric GoldEditor-in-Chief
Updated onOctober 06, 2026
Sesame Care telehealth platform
Sesame Care
VS
TrimRx telehealth platform
TrimRx
Visit Sesame CareVisit TrimRx

Sesame Care vs TrimRx

Complete 2026 Comparison for Weight Loss

Weight Loss

Our Verdict

Sesame Care's weight-loss floor is $208 a month, verified as of 2026-09-12, combining a medication tier with the required care plan. TrimRx starts at $179 a month for compounded semaglutide, verified as of 2026-08-21, and $259 for compounded tirzepatide. That is only $29 a month at entry, so structure matters more than price here. Sesame is a marketplace: you pick a clinician by rating, price and same-day availability, you see the cost before booking, labs and messaging are in the care plan, and insurance is accepted for weight-loss medications. Its other categories are priced per visit, $34 in erectile dysfunction and $37 in hair loss, which is the clearest proof of the model. TrimRx is one program in one category: quiz, consultation, tier, tracked shipping, with no insurance pathway we could verify and no eligibility list on file. Compounded semaglutide and tirzepatide are not FDA-approved as finished products.

Pick Sesame Care

you want to choose the clinician rather than be assigned one, see what a visit costs before you book it, keep labs and messaging inside one care plan, or put insurance to work against the medication cost. It is the only one of the two we can confirm accepts insurance for weight-loss medications. Entry is $208 a month, verified as of 2026-09-12, which is $29 above TrimRx and $51 below TrimRx's tirzepatide tier. Sesame publishes its exclusions, including pregnancy and a history of an active eating disorder.

Pick TrimRx

you want the cheapest entry and the shortest path to it: $179 a month for compounded semaglutide, verified as of 2026-08-21, after a free two-minute quiz and a free doctor consultation, with free tracked shipping. Brand-name Ozempic, Mounjaro, Zepbound and Wegovy are listed as alternatives. You accept that a compounded product is not FDA-approved as a finished product, that we found no insurance pathway, and that no eligibility rules or clinician-selection mechanism appear in our records.

The price question is nearly a tie at entry, and reverses at the tirzepatide tier. The real choice is between a marketplace where you pick the clinician and insurance is in play, and a single program with a fixed route and the lower entry price. Coverage is the tiebreaker: if your plan reaches GLP-1 medication, Sesame is the only one of the two we can confirm will engage with it. If it does not, TrimRx is the cheaper of the two at entry and we have less on file about how its care is structured.

Quick Answer

Best overallTrimRx
Best for convenienceTrimRx

TrimRx is our overall pick for weight loss, based on our rating and feature coverage.

Top Weight Loss Providers

Our Top Choice
1
TrimRx logo

GLP-1 Weight Loss From $179/mo - Free 2-Minute Assessment

  • Compounded GLP-1 (semaglutide) from $179/mo, GLP-1 + GIP (tirzepatide) from $259/mo
  • Brand-name Ozempic®, Mounjaro®, Zepbound® and Wegovy® also available
  • Free 2-minute qualification quiz and FREE doctor consultation - no cost, no obligation
  • Free tracked shipping straight to your door after approval
TrimRx displays LegitScript certificate 31417191, checked September 19, 2026Cert. 31417191September 19, 2026
9.4
OutstandingScore based on review by ManyTreatments editors, popularity, brand reputation, features and benefitsLearn how we score
★★★★★
See PricingRead full review
Most Popular
2
Medvi logo

No Separate Membership Fee Listed on the Compounded Semaglutide Plan (Checked Sep 2026)

  • Doctor-guided compounded GLP-1 care, 100% online. Compounded medications are not FDA-approved and have not been reviewed by the FDA for safety, effectiveness, or quality.
  • Free dietician visits and care coaching included with your plan
  • Doctor-formulated plans adjusted as your body responds
  • Fast, discreet shipping to your door
LegitScript lists Medvi as certified, checked on LegitScript's status page September 20, 2026CertifiedSeptember 20, 2026
9.2
OutstandingScore based on review by ManyTreatments editors, popularity, brand reputation, features and benefitsLearn how we score
★★★★★
See PricingRead full review
3
Fridays logo

Compounded Semaglutide From $150/mo on Prepaid Plans

  • Compounded semaglutide from $150/mo, tirzepatide from $240/mo on prepaid plans
  • Insurance concierge works to maximize your coverage
  • GLP-1 microdosing option and a custom plan in under 3 minutes
Fridays displays LegitScript certificate 18528873, checked September 19, 2026Cert. 18528873September 19, 2026
9.2
OutstandingScore based on review by ManyTreatments editors, popularity, brand reputation, features and benefitsLearn how we score
★★★★★
See PricingRead full review

Provider Overview

Sesame Care logo
9.1

Our editorial rating 9.1/10Trustpilot: 4.6/5 from 4,595 reviews, checked Nov 1, 2026

Sesame Care is a healthcare marketplace connecting patients with doctors for affordable, transparent-priced telehealth and in-person visits across many specialties.

Rating9.1/10
Free ConsultationNo
Free ShippingNo
HSA/FSAYes
Founded2019
HQNew York, NY
Visit Sesame CareRead Full Review
TrimRx logo
9.4

Our editorial rating 9.4/10Trustpilot: 3.4/5 from 4,923 reviews, checked Nov 1, 2026

TrimRx is a telehealth weight loss platform offering compounded GLP-1 medications - semaglutide from $149/month and tirzepatide from $249/month - with licensed physician oversight, sourcing through licensed 503A compounding pharmacies, and a money-back guarantee.

Rating9.4/10
Free ConsultationYes
Free ShippingYes
HSA/FSAYes
Founded2020
HQUnited States
Visit TrimRxRead Full Review
VS

Feature Comparison

Feature comparison between Sesame Care and TrimRx
FeatureSesame CareSesame CareTrimRxTrimRx
Rating9.1/109.4/10
Founded20192020
Free ConsultationNoYes
Free ShippingNoYes
Accepts InsuranceNoNo
HSA/FSA AcceptedYesYes
Mobile AppYesNo
Consultation TypeVideo, In-person, MessagingAsync (text/questionnaire)
Shipping TimeVaries (prescriptions sent to pharmacy)3-5 business days

Pricing Comparison

Pricing comparison between Sesame Care and TrimRx across treatment categories
TreatmentSesame CareTrimRx
Weight Loss$208/month$179/month

Prices shown are starting costs. Actual pricing varies by treatment plan and medication.

Pros and Cons

Sesame Care

Pros

  • Transparent pricing upfront
  • No subscription required
  • Wide range of specialists
  • Both virtual and in-person options
  • Pay-per-visit model

Cons

  • Does not accept insurance
  • Prescriptions filled at external pharmacy
  • No free consultations
  • Prices vary by provider
TrimRx

Pros

  • Lowest price in market at $149/month for semaglutide
  • Money-back guarantee unique in this price range
  • Dispensed through licensed 503A compounding pharmacies
  • 24/7 unlimited support included
  • Can prescribe branded alternatives for insured patients

Cons

  • Weight loss only - no multi-condition coverage
  • Compounded medications are not FDA-approved finished products
  • Does not accept insurance for compounded plans
  • Less brand recognition than Hims or Ro

Which Should You Choose?

Sesame CareChoose Sesame Care if you:
  • Cash-pay patients without insurance
  • Those wanting transparent pricing
  • Patients preferring in-person options
  • Those avoiding subscriptions
Visit Sesame Care
TrimRxChoose TrimRx if you:
  • Patients wanting the lowest monthly GLP-1 cost
  • Those who want a money-back guarantee
  • Patients without insurance who need affordable access
Visit TrimRx

Who This Is For

This is for
  • You want to compare medication options, monthly costs, and state availability across multiple telehealth providers.
  • You prefer reviewing licensed provider programs independently before committing to a subscription.
  • The FDA-approved labeling for Wegovy and Zepbound covers weight reduction in adults with a BMI of 30 or higher, and in adults with a BMI of 27 or higher who have at least one weight-related condition such as type 2 diabetes or high blood pressure. If you are near either number, ask a licensed provider where you fall before choosing a platform.
  • If you are pregnant or planning a pregnancy, the Wegovy label directs you to stop semaglutide once pregnancy is recognized and two months before a planned pregnancy, so raise it at intake.
  • If you are breastfeeding, ask the provider what the label for the specific medication says, because the labels differ.
  • If you have a history of disordered eating, tell the provider at intake, because it is part of what a prescriber weighs before starting a weight loss medication.
  • If you have had bariatric surgery or are considering it, tell the provider at intake, because it changes what a prescriber will consider.
  • A remote visit cannot include a physical exam or in-office testing. If that matters for your situation, raise it with a licensed provider before choosing a platform.
  • If this is an emergency, call 911 or go to the nearest emergency room. Telehealth is not for emergency care.

These notes are not a medical screening: a licensed provider decides after an intake review whether a treatment is appropriate for you.

About This Comparison

Our Editorial Standards

This sesame care vs trimrx provider comparison is independently researched by our editorial team. We compare telehealth services based on publicly available information including pricing, available treatments, and service areas. Our ratings are editorial judgments, not tallies of reviews.

Independent Research: We do not accept payment for rankings or favorable reviews
Affiliate Disclosure: We may earn commissions from qualifying purchases at no extra cost to you
Regular Updates: Content is reviewed and updated monthly for accuracy
Licensed Providers Only: All listed services employ US-licensed healthcare providers

Not Medical Advice: This comparison is for informational purposes only. We are not healthcare providers. Always consult with a licensed physician before starting any treatment. Read our full medical disclaimer and editorial policy.

Independent ResearchNo paid placements
Fact-Checked InformationVerified against official sources
Regularly UpdatedLast updated October 6, 2026
Licensed Providers OnlyAll listed services are US-licensed

Sesame Care vs TrimRx: You Are Choosing a Structure, Not a Price

Eric GoldWritten by Eric GoldEditor-in-Chief
10 min readUpdated October 6, 2026

Table of Contents

$29 a month separates these two at the entry tier, which is close enough that price should not decide it. What should decide it is that they are built differently. Sesame Care is a marketplace: you pick a clinician, you book a visit, the prescription comes out of that visit, and insurance can be in play. TrimRx is a single program: one quiz, one review, one set of monthly tiers. Those are two different purchases that happen to end with similar medication, and a feature grid would bury the difference instead of showing it.

One marketplace, one program: the difference that decides this

The clearest evidence that Sesame is a marketplace is not in its weight-loss listing at all. It is in how Sesame prices its other categories. In erectile dysfunction, Sesame's floor is $34 a visit, verified as of 2026-09-10, not a monthly figure. In hair loss it is $37 a visit, verified as of 2026-07-22, with a monthly subscription offered as an alternative rather than a requirement. A business that prices by the visit is selling you access to a clinician, and the medication follows from that.
Sesame's own listings say the same thing in plainer words: you choose your doctor by rating, price and same-day availability, and you see exactly what you will pay before you book. In weight loss that structure shows up as ongoing video visits with a dedicated provider, labs and messaging bundled into a care plan, with the medication tier priced on top.
TrimRx is the other shape entirely. It appears in our records in exactly one category, weight loss, and it has one path through it: a free two-minute qualification quiz, a free doctor consultation, then a monthly tier and free tracked shipping once you are approved. Sesame appears in three categories in our records. TrimRx appears in one, and does that one thing with a fixed route through it.
Neither shape is better in the abstract. One of them is better for you, and which one depends on whether you want to steer or whether you want the steering done.

What $208 and $179 actually describe

Sesame's weight-loss floor is $208 a month, verified as of 2026-09-12. That number is a medication tier plus a care plan, both required, and Sesame advertises them as two separate lines. We publish the combined figure because that is the one that leaves your account. TrimRx starts at $179 a month for compounded semaglutide, verified as of 2026-08-21, with a compounded tirzepatide tier starting at $259 a month.
That puts $29 a month between the two entry prices. Over a year, if you stay at entry on both, the difference is $348. It is real money and it is also small enough that it should lose to any structural preference you actually hold. If you compare Sesame against TrimRx's tirzepatide tier, the ordering flips and Sesame is $51 a month cheaper.
Neither figure is a quote.
  • Sesame Care weight loss: from $208 a month, medication tier plus required care plan, verified as of 2026-09-12
  • TrimRx compounded semaglutide: from $179 a month, verified as of 2026-08-21
  • TrimRx compounded tirzepatide: from $259 a month
  • Entry gap: $29 a month in TrimRx's favor, or $51 a month in Sesame's favor at the tirzepatide tier

The insurance fork in the road

Sesame's weight-loss listing names cash-pay GLP-1 medications and states that insurance is accepted for weight-loss medications. Its care plan covers ongoing video visits, a dedicated provider, labs and messaging. Sesame also says it fits you best if you have a BMI over 27 and want access to GLP-1 medications such as Wegovy or Zepbound, or if you are uninsured and want predictable pricing. That is an unusual pair to serve at once, and it works only because the marketplace prices both ways.
TrimRx's listing says nothing about insurance, and we did not verify whether it accepts any. Read that as unknown rather than as a no. If you hold coverage that reaches GLP-1 medication, Sesame is the only one of the two we can confirm will engage with it, and that single fact can dwarf a monthly difference of that size in either direction depending on what your plan does.
If you have no coverage, the insurance column goes blank for both and you are back to comparing the two floors and deciding whether labs and a dedicated provider are worth the gap.

Choosing your own clinician against being assigned one

On Sesame you choose. Clinicians are listed with a rating, a price and their same-day availability, and you book the one you want, then keep seeing a dedicated provider through the care plan. Same-day visits are part of the pitch, and the cost of the visit is shown before you commit to it. If you have ever wanted to read a clinician's profile before handing over your medical history, that is the feature.
On TrimRx you do not choose. A free doctor consultation follows the quiz, and our records name no mechanism for selecting, rating or switching the clinician, and no ongoing-care package as a line item. That is not a criticism of the care, which we did not assess. It is a statement about what is defined in writing and what is not, and it is the thing to ask about before paying if continuity matters to you.
On the medication itself the two overlap more than their structures suggest. TrimRx lists compounded semaglutide and compounded tirzepatide alongside brand-name Ozempic, Mounjaro, Zepbound and Wegovy. Compounded medications of that kind are not FDA-approved as finished products and the FDA has not reviewed them for safety, effectiveness or quality, so if you are routed to a compounded tier you should know that is what you are holding. Sesame's weight-loss listing does not name a compounded option at all, and we did not verify whether one exists, so we are not going to tell you either way.

Where this comparison runs out of verified ground

Sesame publishes who it is not for, and we hold the list: not if you are pregnant, since GLP-1 medications are contraindicated in pregnancy; not if you have a history of an active eating disorder that needs specialized treatment at a clinic; and not if what you need is a bariatric surgery evaluation, which requires surgical care face to face.
For TrimRx we hold no eligibility list, no BMI threshold and no exclusion set. That is a gap in our records rather than a finding about the brand, and we would rather show you the gap than invent something plausible to fill it.
Our scores put TrimRx at 9.4 out of 10, which we label Outstanding, and Sesame Care at 9.1 out of 10, which we label Excellent. That margin is too narrow to call a winner on, and we did not find a single feature in either listing that would overturn the structural choice described at the top of this page.
Nothing here is medical advice, and nothing here is a recommendation to take or request any particular medication. Both brands put a clinician between you and a prescription, which is the part of both models that actually matters.

How We Compared Sesame Care vs TrimRx

How we compared these two

This page deliberately avoids a feature grid, because a grid implies the two brands are the same kind of thing priced differently, and they are not. One sells clinician visits, the other sells a program.

Where the structural claim comes from. We did not take Sesame's word that it is a marketplace. We read how it prices every category we hold for it: $34 a visit in erectile dysfunction, verified as of 2026-09-10, and $37 a visit in hair loss, verified as of 2026-07-22, both priced per visit rather than per month, with clinicians listed by rating, price and availability. Per-visit pricing across categories is what a marketplace looks like from the outside. TrimRx appears in one category only, weight loss, with one route through it.

Prices. We publish one verified monthly floor per brand per category and the date we last verified it. Sesame Care weight loss: $208 a month, verified as of 2026-09-12. TrimRx weight loss: $179 a month, verified as of 2026-08-21. Where a brand splits a required care plan from the medication in its advertising, we combine them, because the combined figure is what you are billed. We never publish below the verified floor.

Scores. TrimRx 9.4 out of 10, Sesame Care 9.1 out of 10, both from our own brand record.

What we left out. No outcome figures, no pounds, no percentages, no timelines. We also left out any volume or satisfaction statistic that we could not independently verify, and we left TrimRx's eligibility rules blank because we hold none.

Final Verdict: Sesame Care vs TrimRx

The verdict

Sesame Care if you want to steer. You pick the clinician, you see the visit price before booking, same-day availability is part of the offer, labs and messaging sit inside the care plan, and insurance is accepted for weight-loss medications. That costs $29 a month more than TrimRx at entry, $208 against $179, and it is cheaper than TrimRx's tirzepatide tier by $51 a month.

TrimRx if you want the steering done. One quiz, one consultation, one tier, free tracked shipping, and the lowest entry number of the two. You accept a compounded product that is not FDA-approved as a finished product if that is the tier you are placed on, you get no insurance pathway that we could verify, and we have no eligibility rules on file to show you in advance.

The honest summary is that a gap that small is not enough to override a preference about how you want to buy care. Decide the structure first and let the price follow. If you hold GLP-1 coverage, that decision is already made for you.

Visit Sesame CareVisit TrimRx

Frequently Asked Questions

Is Sesame Care cheaper than TrimRx for weight loss?

Not at the entry tier. Sesame's weight-loss floor is $208 a month, verified as of 2026-09-12, which combines a medication tier with the care plan it requires. TrimRx starts at $179 a month for compounded semaglutide, verified as of 2026-08-21. That is $29 a month in TrimRx's favor, or $348 over a year. Compare Sesame against TrimRx's $259 compounded tirzepatide tier and Sesame is $51 a month cheaper.

Does Sesame Care take insurance for GLP-1 medication?

Sesame's weight-loss listing states that insurance is accepted for weight-loss medications, and it also lists cash-pay GLP-1 options for anyone without coverage. What your specific plan covers is between you and your insurer, so check it before you book. TrimRx's listing says nothing about insurance and we did not verify whether it accepts any.

Do I have to pay a monthly membership with Sesame Care?

For weight loss, the care plan is part of the floor we publish, which is why our figure is the combined one rather than the smaller medication-only number Sesame advertises alongside it. Sesame's other categories work differently and are priced per visit, $34 a visit in erectile dysfunction as of 2026-09-10 and $37 a visit in hair loss as of 2026-07-22, with a subscription offered as an option rather than a requirement.

Is TrimRx semaglutide FDA approved?

Compounded semaglutide is not FDA-approved as a finished product, and the FDA has not reviewed it for safety, effectiveness or quality. The same is true of compounded tirzepatide. TrimRx does separately list brand-name Ozempic, Mounjaro, Zepbound and Wegovy, so ask which of the two routes the price you are quoted refers to.

Can I pick my own doctor on either of these?

On Sesame, yes. Clinicians are listed with a rating, a price and same-day availability, and you book the one you choose, then continue with a dedicated provider under the care plan. On TrimRx our records name no selection or switching mechanism, only a free doctor consultation after the qualification quiz.

Sources & References

Our comparisons are informed by official sources and regulatory guidelines. We encourage you to verify information with authoritative sources.

    Editorial Note: Researched and edited by our editorial team. AI tools assist with initial research and drafting; all content is fact-checked and edited by humans before publication. Learn more about our editorial standards

    Related Comparisons

    HimsVSSesame CareHimsVSTrimRxHersVSSesame CareHersVSTrimRxRoVSSesame CareRoVSTrimRx

    Start With a Top Weight Loss Provider

    Our Top Choice
    1
    TrimRx logo

    GLP-1 Weight Loss From $179/mo - Free 2-Minute Assessment

    • Compounded GLP-1 (semaglutide) from $179/mo, GLP-1 + GIP (tirzepatide) from $259/mo
    • Brand-name Ozempic®, Mounjaro®, Zepbound® and Wegovy® also available
    • Free 2-minute qualification quiz and FREE doctor consultation - no cost, no obligation
    • Free tracked shipping straight to your door after approval
    TrimRx displays LegitScript certificate 31417191, checked September 19, 2026Cert. 31417191September 19, 2026
    9.4
    OutstandingScore based on review by ManyTreatments editors, popularity, brand reputation, features and benefitsLearn how we score
    ★★★★★
    See PricingRead full review
    Most Popular
    2
    Medvi logo

    No Separate Membership Fee Listed on the Compounded Semaglutide Plan (Checked Sep 2026)

    • Doctor-guided compounded GLP-1 care, 100% online. Compounded medications are not FDA-approved and have not been reviewed by the FDA for safety, effectiveness, or quality.
    • Free dietician visits and care coaching included with your plan
    • Doctor-formulated plans adjusted as your body responds
    • Fast, discreet shipping to your door
    LegitScript lists Medvi as certified, checked on LegitScript's status page September 20, 2026CertifiedSeptember 20, 2026
    9.2
    OutstandingScore based on review by ManyTreatments editors, popularity, brand reputation, features and benefitsLearn how we score
    ★★★★★
    See PricingRead full review
    3
    Fridays logo

    Compounded Semaglutide From $150/mo on Prepaid Plans

    • Compounded semaglutide from $150/mo, tirzepatide from $240/mo on prepaid plans
    • Insurance concierge works to maximize your coverage
    • GLP-1 microdosing option and a custom plan in under 3 minutes
    Fridays displays LegitScript certificate 18528873, checked September 19, 2026Cert. 18528873September 19, 2026
    9.2
    OutstandingScore based on review by ManyTreatments editors, popularity, brand reputation, features and benefitsLearn how we score
    ★★★★★
    See PricingRead full review

    Related Resources

    Brand Review

    Sesame Care Review

    Brand Review

    TrimRx Review

    Brand Review

    Is Sesame Care Legit?

    Brand Review

    Is TrimRx Legit?

    Guide

    Sesame Care Alternatives

    Guide

    TrimRx Alternatives

    Eric Gold
    Eric GoldEditor-in-Chief

    Eric Gold is a writer and editor with a background in digital media and consumer research. He has spent the last several years covering the health and wellness industry, with a particular focus on telehealth services and direct-to-consumer healthcare. Eric believes that access to clear, unbiased information should not require a medical degree. When he is not reviewing telehealth platforms, he enjoys hiking, cooking, and following the stock market a little too closely.

    Medical Disclaimer: The information on this page is for educational purposes only and is not medical advice. Always consult with a licensed healthcare provider before starting any treatment. Read our full medical disclaimer.

    How we scoreOur 1 to 10 brand scores are our own editorial judgment. They are not aggregated from third-party review platforms and they are not the output of a scoring formula.

    What a starting price isA starting price is the lowest figure a company lists for a category, not a quote. What you pay follows a clinician's review of your intake, and where a required membership or care plan sits alongside the medication we publish the two charges combined.

    Reading a warning letterA close-out letter is FDA's record that it has evaluated a company's corrective actions, so the absence of one means the file is not closed on the public record, and nothing more than that.

    Regulatory noticeRegulatory note (verified October 8, 2026): On February 20, 2026 the FDA issued MEDVi, LLC a warning letter (MARCS-CMS 721455) citing misbranding under sections 502(a) and 502(bb) of the FD&C Act. Reviewing medvi.io in December 2025, the FDA said labels bearing "MEDVi" implied MEDVi compounds the drugs when it does not, and that site copy presenting the compounded drug as having the same active ingredient as Wegovy and Ozempic, and as Mounjaro and Zepbound, implied an FDA approval compounded drugs do not have. The letter adds that introducing or delivering the products it identifies into interstate commerce is a prohibited act under section 301(a), that receiving them in interstate commerce and delivering or offering to deliver them also violates section 301(c), and that a compounded drug product must meet the conditions of section 503A or 503B of the FD&C Act to be exempt from certain requirements, including the new drug approval requirements. When we checked FDA's warning letter index for MEDVi, LLC on October 8, 2026 it showed no response letter and no close-out letter entered against it, so the letter is not closed out on the public record. MEDVi states medvi.io is affiliate-operated rather than company-operated; we could not verify that, and the letter is addressed to MEDVi, LLC. Read the FDA letter