Skinny.Rx is a telehealth platform focused exclusively on GLP-1 weight loss medications, offering compounded semaglutide and tirzepatide at competitive prices with nationwide availability across all 50 states.
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Complete 2026 Comparison for Weight Loss
TrimRx is our overall pick for weight loss, based on ratings, reviews, and feature coverage.
Skinny.Rx is a telehealth platform focused exclusively on GLP-1 weight loss medications, offering compounded semaglutide and tirzepatide at competitive prices with nationwide availability across all 50 states.
TrimRx is a telehealth weight loss platform offering compounded GLP-1 medications - semaglutide from $149/month and tirzepatide from $249/month - with licensed physician oversight, FDA-registered 503B pharmacy sourcing, and a money-back guarantee.
| Feature | ||
|---|---|---|
| Rating | 8.6/5 | 9.2/5 |
| Reviews | 4,900 | 350,000 |
| Founded | 2024 | 2020 |
| Free Consultation | Yes | Yes |
| Free Shipping | Yes | Yes |
| Accepts Insurance | No | No |
| HSA/FSA Accepted | Yes | Yes |
| Mobile App | No | No |
| Consultation Type | Asynchronous | Async (text/questionnaire) |
| Shipping Time | 3-5 business days | 3-5 business days |
| Treatment | ||
|---|---|---|
| Weight Loss | $149/month$149-$299/month | $149/mo$149-$249/mo |
The better choice depends on your specific needs and priorities. Skinny.Rx (rated 8.6/5 from 4,900 reviews) is best for patients seeking affordable glp-1 weight loss treatment. TrimRx (rated 9.2/5 from 350,000 reviews) excels at patients wanting the lowest monthly glp-1 cost. Skinny.Rx was founded in 2024 in United States, while TrimRx was founded in 2020 in United States. Both are legitimate, licensed telehealth providers with board-certified physicians.
Pricing varies by treatment category. Skinny.Rx starts at $149/month (range: $149-$299/month). TrimRx starts at $149/mo (range: $149-$249/mo). Skinny.Rx offers free consultations. TrimRx offers free consultations. Skinny.Rx provides free shipping. TrimRx provides free shipping. Both platforms accept HSA/FSA payments for eligible treatments.
Skinny.Rx does not accept health insurance, operating on a cash-pay model with transparent pricing. TrimRx does not accept insurance. Both platforms accept HSA (Health Savings Account) and FSA (Flexible Spending Account) payments for eligible medical expenses. Many users find that cash-pay telehealth prices are competitive with or lower than insurance copays, especially for generic medications.
Yes, both Skinny.Rx and TrimRx are legitimate, licensed telehealth platforms. Skinny.Rx was founded in 2024 and is headquartered in United States. TrimRx was founded in 2020 in United States. Both employ board-certified physicians licensed in your state, follow HIPAA regulations for patient privacy, and partner with licensed pharmacies to fulfill prescriptions. You can verify their credentials through state medical boards and pharmacy licensing authorities.
Skinny.Rx offers asynchronous consultations (free). TrimRx provides async (text/questionnaire) consultations (free). Both platforms allow you to complete a health questionnaire online, which is reviewed by a licensed healthcare provider. Response times are typically within 24-48 hours, and you can message your provider with follow-up questions through the platform.
Skinny.Rx ships within 3-5 business days with free standard shipping. TrimRx ships within 3-5 business days with free standard shipping. Both platforms use discreet packaging with no indication of the contents. Medications are shipped directly from licensed pharmacies to your door.
Skinny.Rx requires a subscription for most treatments and allows you to cancel anytime without fees. TrimRx also uses a subscription model with no cancellation penalties. Both platforms allow you to pause, modify, or cancel your subscription through your online account. Note that you should cancel before your next billing date to avoid being charged for the following period. Any medications already shipped will still be delivered.
Both offer GLP-1 weight loss medications. Skinny.Rx provides Compounded Semaglutide, Compounded Tirzepatide starting at $149/month. TrimRx offers Compounded Semaglutide, Compounded Tirzepatide starting at $149/mo. Both platforms offer compounded semaglutide, which is the same active ingredient as Ozempic and Wegovy. Clinical studies show GLP-1 medications can help patients lose 15-20% of body weight. Programs typically include medication, provider consultations, and ongoing support. Results vary based on adherence, diet, and lifestyle factors.
Side effects depend on the medication, not the platform, since both Skinny.Rx and TrimRx prescribe the same FDA-approved medications. Common side effects vary by treatment: ED medications may cause headaches, flushing, or nasal congestion; finasteride for hair loss may affect libido in 1-2% of users; GLP-1 weight loss medications commonly cause nausea, especially initially; SSRIs for mental health may cause drowsiness or changes in appetite. Both platforms have licensed physicians who review your medical history to ensure treatments are safe for you and monitor for any adverse effects.
Choose Skinny.Rx if you prioritize: patients seeking affordable glp-1 weight loss treatment, those wanting a simple, focused weight loss platform. Choose TrimRx if you prioritize: patients wanting the lowest monthly glp-1 cost, those who want a money-back guarantee. Skinny.Rx stands out for: Exclusively focused on GLP-1 weight loss. TrimRx is known for: Money-back guarantee if you do not lose weight. Both are reputable telehealth providers - your choice may come down to pricing, specific treatment options, or user experience preferences.
Getting started with either platform is straightforward. For Skinny.Rx: Visit their website, select your treatment category, complete a health questionnaire, and a licensed provider will review your information within 24-48 hours. For TrimRx: Follow a similar process on their platform. Both require you to provide your medical history, current medications, and answer health screening questions. If approved, your prescription is sent to a licensed pharmacy and shipped to your door (often with free shipping). The entire process from signup to receiving medication typically takes 3-7 days.
Skinny.Rx has a 8.6/5 rating from 4,900 reviews on Trustpilot. Customers praise: competitive pricing on glp-1 medications. Common complaints include: weight loss only — no other treatment categories. TrimRx has a 9.2/5 rating from 350,000 reviews on TrimRx.com (self-reported). Customers appreciate: lowest price in market at $149/month for semaglutide. Some note: weight loss only - no multi-condition coverage. Both platforms have the positive reviews typical of established telehealth providers and responsive customer service teams.
Medical Disclaimer: The information on this page is for educational purposes only and is not medical advice. Always consult with a licensed healthcare provider before starting any treatment. Read our full medical disclaimer.