Skinny.Rx is a telehealth platform focused exclusively on GLP-1 weight loss medications, offering compounded semaglutide and tirzepatide at competitive prices with nationwide availability across all 50 states.
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Complete 2026 Comparison for Weight Loss
Skinny.Rx is a telehealth platform focused exclusively on GLP-1 weight loss medications, offering compounded semaglutide and tirzepatide at competitive prices with nationwide availability across all 50 states.
Shed is a telehealth platform focused on weight loss treatment, offering GLP-1 medications including compounded semaglutide and tirzepatide through a full wellness program.
| Feature | ||
|---|---|---|
| Rating | 9/10 | 9/10 |
| Founded | 2024 | 2024 |
| Free Consultation | Yes | Yes |
| Free Shipping | Yes | Yes |
| Accepts Insurance | No | No |
| HSA/FSA Accepted | Yes | Yes |
| Mobile App | No | No |
| Consultation Type | Asynchronous | Video, Asynchronous |
| Shipping Time | 3-5 business days | 3-5 business days |
| Treatment | ||
|---|---|---|
| Weight Loss | $149.25/month$149.25-$299/month | $159/mo$159-$399/mo |
The better choice depends on your specific needs and priorities. Skinny.Rx carries a 8.6/10 rating in our provider database and is listed as a fit for patients seeking affordable glp-1 weight loss treatment. Shed carries a 9.2/10 rating in our provider database and is listed as a fit for those seeking glp-1 weight loss medications. Those scores are our own editorial ratings, not third-party review averages. Skinny.Rx was founded in 2024 in United States, while Shed was founded in 2024 in New York, NY. Both are US telehealth platforms that connect you with licensed providers, and which one suits you is a question for that provider.
Pricing varies by treatment category. Skinny.Rx starts at $149.25/month (range: $149.25-$299/month). Shed starts at $159/mo (range: $159-$399/mo). These are the rates last recorded in our provider database, so confirm the current price at checkout before you enroll. Skinny.Rx lists free consultations. Shed lists free consultations. Skinny.Rx lists free shipping. Shed lists free shipping. Skinny.Rx and Shed list HSA and FSA payment options, though whether a given charge is eligible depends on your plan and on IRS rules for that expense.
Skinny.Rx does not list health insurance as accepted, and operates on a cash-pay model with published pricing. Shed does not list insurance as accepted. Skinny.Rx and Shed list HSA and FSA payment options; eligibility for any specific charge depends on your plan and IRS rules, so check with your plan administrator first. Coverage and pricing change, so confirm both with the platform and your insurer before you enroll.
Both are established US telehealth platforms. Skinny.Rx was founded in 2024 and is headquartered in United States. Shed was founded in 2024 in New York, NY. Both state that they work with US-licensed providers and licensed pharmacies and that they operate under HIPAA. We do not independently audit provider credentials or pharmacy licensing, so if you want that confirmed, you can look up an individual prescriber through your state medical board and a pharmacy through your state board of pharmacy.
Skinny.Rx offers asynchronous consultations (free). Shed provides video and asynchronous consultations (free). On both, you complete a health questionnaire online that a licensed provider reviews. Video consultations are available if you prefer to speak with a provider face to face. Turnaround times vary by platform, by state, and by how busy the provider network is, and you can message your provider with follow-up questions through the platform.
Skinny.Rx lists shipping within 3-5 business days with free standard shipping. Shed lists shipping within 3-5 business days with free standard shipping. Both describe discreet packaging, and medications ship from licensed pharmacies rather than from the platform itself. Actual delivery time depends on your state, the pharmacy, and whether your prescription needs follow-up.
Skinny.Rx requires a subscription for most treatments and lists cancellation at any time without a fee. Shed also uses a subscription model and lists no cancellation penalty. Cancellation terms are set by each platform and can change, so read the current terms before you enroll. As a general rule you need to cancel before your next billing date to avoid the following period's charge, and anything already shipped is still yours.
Skinny.Rx lists Compounded Semaglutide, Compounded Tirzepatide starting at $149.25/month. Shed lists Compounded Semaglutide, Compounded Tirzepatide starting at $159/mo. Wegovy (semaglutide) and Zepbound (tirzepatide) are the brand-name injectables FDA-approved for weight management. Where a program dispenses compounded semaglutide or tirzepatide instead, that is a pharmacy-prepared drug rather than the approved finished product. Compounded drugs are not FDA-approved and have not been reviewed by the FDA for safety, effectiveness, or quality. Programs typically bundle medication, provider consultations, and check-ins, and they differ mainly on price, on which medications they carry, and on how much support is included. Whether any of this is appropriate for you is a question for a licensed provider.
Side effects come from the medication, not from the platform, so this is mostly a question about the drug you end up on rather than about Skinny.Rx versus Shed. Reported effects vary by treatment: ED medications may cause headache, flushing, or nasal congestion; finasteride carries labeled sexual side effects that some men report persisting after they stop; GLP-1 medications commonly cause nausea, vomiting, and other gastrointestinal effects, especially when the dose goes up; SSRIs may cause drowsiness, nausea, or changes in appetite and sexual function. This is not the full list for any of them. Both platforms have licensed providers review your medical history and screen for contraindications, and you should read the medication guide and raise anything you notice with your provider.
Choose Skinny.Rx if you prioritize: patients seeking affordable glp-1 weight loss treatment, those wanting a simple, focused weight loss platform. Choose Shed if you prioritize: those seeking glp-1 weight loss medications, patients wanting a whole-health approach. Skinny.Rx stands out for: Exclusively focused on GLP-1 weight loss. Shed is known for: Wellness-focused weight loss approach. Both are established telehealth platforms, so your choice mostly comes down to price, which treatments each one carries, and how you prefer to handle visits and refills.
The process is similar on both. For Skinny.Rx: visit their website, select your treatment category, and complete a health questionnaire that a licensed provider reviews. For Shed: follow the same kind of flow on their platform. Both ask for your medical history, current medications, and answers to health screening questions, and being straight with those answers is what lets the provider catch an interaction. If you are approved, the prescription goes to a licensed pharmacy and ships to you (often with free shipping). How long the whole thing takes depends on the platform, your state, and the pharmacy.
Skinny.Rx carries a 8.6/10 rating in our provider database, and Shed carries a 9.2/10 rating in our provider database. Those are ManyTreatments editorial scores on a 10-point scale, not averages pulled from third-party review sites, and you can read how we build them on our how-we-rate page. What we weigh: Skinny.Rx scores well on competitive pricing on glp-1 medications, with weight loss only - no other treatment categories as the trade-off. For Shed it is free initial consultation, against limited to weight loss. If you want customer sentiment as well, check current listings on the review platforms directly, since those move.
Medical Disclaimer: The information on this page is for educational purposes only and is not medical advice. Always consult with a licensed healthcare provider before starting any treatment. Read our full medical disclaimer.
Regulatory noticeRegulatory note (verified August 22, 2026): Skinny.Rx operates as SkinnyRx, but the legal entity is Lean Rx, Inc., and that is the name on FDA warning letter MARCS-CMS 717989, dated February 20, 2026. Following a December 2025 review of skinnyrx.com, the agency objected to the "SkinnyRx" name on pictured labels, saying it implies SkinnyRx compounds the drugs itself, and to three marketing lines, including "Get access to the same active ingredient as name-brand GLP-1 medications" and "It contains the same active ingredient as FDA-approved medications." Compounded semaglutide and tirzepatide are not FDA-approved, so the FDA read those lines as implying an approval that does not exist and classed the products as misbranded. No close-out letter is posted; read the matter as unresolved. Read the FDA letter
Regulatory noticeRegulatory note (verified August 22, 2026): On February 20, 2026 the FDA issued MEDVi, LLC a warning letter (MARCS-CMS 721455) citing misbranding under sections 502(a) and 502(bb) of the FD&C Act. Reviewing medvi.io in December 2025, the FDA said labels bearing "MEDVi" implied MEDVi compounds the drugs when it does not, and that "Same active ingredient as Wegovy and Ozempic" and "Same active ingredient as Mounjaro and Zepbound" implied an FDA approval compounded drugs do not have. We found no close-out letter, so the matter appears open. MEDVi states medvi.io is affiliate-operated rather than company-operated; we could not verify that, and the letter is addressed to MEDVi, LLC. Read the FDA letter